This Article Full Text (OnlineFirst PDF) Alert me when this article is cited Alert me if a correction is posted Services Email this article to a friend Similar articles in this journal Similar articles in PubMed Alert me to new issues of the journal Add to Saved Citations Download to citation manager Request Permissions Request Reprints Add to My Marked Citations Citing Articles Citing Articles via Google Scholar Google Scholar Articles by Ribeiro, J. L. Articles by Roisenberg, I. Search for Related Content PubMed PubMed Citation Articles by Ribeiro, J. L. Articles by Roisenberg, I. Social Bookmarking                   What's this?

The Effect of ABO Blood Group on von Willebrand Response to Exercise

Federal University of Rio Grande do Sul

^* To whom correspondence should be addressed. E-mail: jerriribeiro{at}yahoo.com.br.

	Abstract

Individuals of O blood group have significantly lower plasma levels of either Factor VIII (FVIII) or the von Willebrand factor (vWF). Conversely, there is accumulating evidence that elevated FVIII–vWF levels may represent an important risk factor for ischemic heart and venous thromboembolic disease. In this study, individuals exercised for 20 minutes at 10% below the first ventilatory threshold (aerobic threshold), which corresponds to 48% of maximum oxygen uptake. People with non-O blood group show higher resting and postexercise vWF levels compared with those of O blood group, as evidenced by a lower maximal heart rate. The groups were compared using the ANOVA one-way test, and a P < 0.05 was considered statistically significant. These results could change the way in which exercise training is designed for both healthy and sick individuals because O group individuals could have a more thrombogenic response to exercise.

CiteULike    Connotea    Del.icio.us    Digg    Reddit    Technorati    What's this?