Clinical and Applied Thrombosis/Hemostasis

 

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First published on April 2, 2008
Clinical and Applied Thrombosis/Hemostasis 2008, doi:10.1177/1076029608315166
© 2008 SAGE Publications

Article

Myocardial Infarction in a 28-Year-Old Thalassemia Intermedia Patient

Fuad El Rassi*, Hussein Ismaeel, Suzanne Koussa, and Ali Taher

* To whom correspondence should be addressed. E-mail: fuadrassi{at}gmail.com.


  Abstract
A 28-year-old Lebanese thalassemia intermedia (TI) patient with homozygous IVS1-110 mutation sustained atypical chest pain of 1 day’s duration. The EKG reading revealed ST segment elevation in the chest leads V1 to V5. Coronary angiography showed 2 plaques in the left anterior descending coronary artery. He underwent subsequent angioplasty with stenting of the left anterior descending coronary artery. An extensive thrombophilia profile was negative. He was started on medication, and his medical condition improved and chest pain ceased. This is the first case report of myocardial infarction in a TI patient among thalassemics. We propose that such cases will emerge more frequently as our population ages, keeping in mind a possible thrombotic mechanism.


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