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A Prospective Comparison of New Japanese Criteria for Disseminated Intravascular Coagulation

New Japanese Criteria Versus ISTH Criteria

Division of Acute and Critical Care Medicine, Department of Anesthesiology and Critical Care Medicine, Hokkaido University Graduate School of Medicine, N15 W7, Kita-ku, Sapporo 060-8638, Japan, mineji{at}dream.com

Satoshi Gando, MD, PhD

Division of Acute and Critical Care Medicine, Department of Anesthesiology and Critical Care Medicine, Hokkaido University Graduate School of Medicine, N15 W7, Kita-ku, Sapporo 060-8638, Japan

Hirokatsu Hoshino, MD

Division of Acute and Critical Care Medicine, Department of Anesthesiology and Critical Care Medicine, Hokkaido University Graduate School of Medicine, N15 W7, Kita-ku, Sapporo 060-8638, Japan

In Japan, early diagnosis and early treatment of disseminated intravascular coagulation (DIC) based on the old Japanese criteria have greatly improved the outcomes of DIC patients with hematopoietic malignancy. However, the prognoses of critically ill patients with DIC have remained poor. To overcome this situation, new Japanese DIC criteria for critically ill patients were established in 2002. The new Japanese DIC criteria adopted a concept of coagulopathy associated with systemic inflammatory response syndrome. In the present study, we prospectively investigated the relationships between the new criteria and organ failure, prognosis, and other sets of DIC criteria. This study included 74 patients whose platelet counts were below 150 x 10⁹/L. Daily DIC scores and sequential organ failure assessment scores were recorded from days 0 to 4 once the patient was included

Key Words: Disseminated intravascular coagulation • Diagnostic criteria • Japan • International Society on Thrombosis and Haemostasis • Hemostatic disorders • Systemic inflammatory response syndrome.

Clinical and Applied Thrombosis/Hemostasis, Vol. 13, No. 2, 172-181 (2007)
DOI: 10.1177/1076029606299077


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