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Clinical and Applied Thrombosis/Hemostasis
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Heparin-Induced Thrombocytopenia Complicating Hemodialysis

M.F. Barginear, MD

Don Monti Division of Medical Oncology/Division of Hematology North Shore University Hospital, New York University School of Medicine, New York, Transplant Services, Division of Kidney Diseases and Hypertension North Shore University Hospital, New York University School of Medicine, New York, m_barginear{at}hotmail.com

L. Donahue, MD

Don Monti Division of Medical Oncology/Division of Hematology North Shore University Hospital, New York University School of Medicine, New York

S.L. Allen, MD

Don Monti Division of Medical Oncology/Division of Hematology North Shore University Hospital, New York University School of Medicine, New York

D.R. Budman, MD, FACP

Don Monti Division of Medical Oncology/Division of Hematology North Shore University Hospital, New York University School of Medicine, New York

T. Bradley, MD

Don Monti Division of Medical Oncology/Division of Hematology North Shore University Hospital, New York University School of Medicine, New York

M. Bhaskaran, MD

Don Monti Division of Medical Oncology/Division of Hematology North Shore University Hospital, New York University School of Medicine, New York

I. Shapira, MD

Don Monti Division of Medical Oncology/Division of Hematology North Shore University Hospital, New York University School of Medicine, New York

Hemodialysis complicated by heparin-induced thrombocytopenia (HIT) is a rare event requiring anticoagulation with direct-thrombin inhibitors. Contaminant calcific uremic arteriolopathy (calciphylaxis) further complicates this situation due to the possibility that warfarin anticoagulation may exacerbate skin necrosis. The authors report a patient with renal failure and calciphylaxis who developed HIT after starting hemodialysis. She was successfully treated with Argatroban.

Key Words: heparin-induced thrombocytopenia • hemodialysis • thrombosis

This version was published on January 1, 2008

Clinical and Applied Thrombosis/Hemostasis, Vol. 14, No. 1, 105-107 (2008)
DOI: 10.1177/1076029607304405
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