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Bilateral Subdural Hematomas in an Adult With Hereditary Factor VII Deficiency: A Complication of Sit-ups and Inversion?

Southern Iron Disorders Center, Department of Medicine, University of Alabama at Birmingham, ironmd{at}dnamail.com

Luigi F. Bertoli, MD

Southern Iron Disorders Center, Department of Medicine, Brookwood Medical Center

Sean O'Malley, MD

Department of Surgery, Brookwood Medical Center, Birmingham, Alabama

A 57-year-old man of northern Italian and Polish descent with a late-onset, mild form of hereditary factor VII deficiency developed bilateral intracranial subdural hematomas after performing sit-ups while he was in a head-down position on an inversion table. The pertinence of the Valsalva maneuver and increased intracranial venous and intraocular pressure associated with sit-ups and other exercises in the causation of subdural hematomas and other types of intracranial and ocular hemorrhage are discussed in this study.

Key Words: intracranial hemorrhage • recombinant factor VIIa • Valsalva maneuver

This version was published on April 1, 2009

Clinical and Applied Thrombosis/Hemostasis, Vol. 15, No. 2, 242-244 (2009)
DOI: 10.1177/1076029607308862


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