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Clinical and Applied Thrombosis/Hemostasis
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*Heart Attack
*Thalassemia
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Myocardial Infarction in a 28-Year-Old Thalassemia Intermedia Patient

Fuad A. El Rassi, MD

American University of Beirut Medical Center, Beirut

Hussain A. Ismaeel, MD

American University of Beirut Medical Center, Beirut

Suzanne C. Koussa, MD

Chronic Care Center, Hazmieh Lebanon

Ali T. Taher, MD

American University of Beirut Medical Center, Beirut, ataher{at}aub.edu.lb, Chronic Care Center, Hazmieh Lebanon

A 28-year-old Lebanese thalassemia intermedia (TI) patient with homozygous IVS1-110 mutation sustained atypical chest pain of 1 day’s duration. The EKG reading revealed ST segment elevation in the chest leads V1 to V5. Coronary angiography showed 2 plaques in the left anterior descending coronary artery. He underwent subsequent angioplasty with stenting of the left anterior descending coronary artery. An extensive thrombophilia profile was negative. He was started on medication, and his medical condition improved and chest pain ceased. This is the first case report of myocardial infarction in a TI patient among thalassemics. We propose that such cases will emerge more frequently as our population ages, keeping in mind a possible thrombotic mechanism.

Key Words: myocardial infarction • thalassemia intermedia • thrombosis • pulmonary hypertension

This version was published on August 1, 2009

Clinical and Applied Thrombosis/Hemostasis, Vol. 15, No. 4, 467-469 (2009)
DOI: 10.1177/1076029608315166
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