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Clinical and Applied Thrombosis/Hemostasis
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Sinus Venous Thrombosis Associated with a Nephrotic Syndrome in an Eight-Year-Old Child

Yolanda Mira, M.D.

Department of Clinical Pathology, University Hospital "La Fe"

Santiago Mendizabal, M.D.

Service of Pediatric Nephrology, University Hospital "La Fe," Valencia, Spain

Amparo Vayá, M.D.

Department of Clinical Pathology, University Hospital "La Fe"

Nuria Sanchis, M.D.

Service of Pediatric Nephrology, University Hospital "La Fe," Valencia, Spain

Piedad Villa, M.D.

Department of Clinical Pathology, University Hospital "La Fe"

Justo Aznar, M.D.

Department of Clinical Pathology, University Hospital "La Fe"

The nephrotic syndrome (NS) is reportedly as sociated with an increased risk of thromboembolic dis ease. We describe the case of an 8-year-old child with a steroid-responsive NS who developed a longitudinal si nus venous thrombosis. No family thrombophilic ten dency was found. To our knowledge, this is the second case published with these clinical characteristics. We sug gest that the sinus venous thrombosis was precipitated by the low levels of antithrombin III and hypoalbuminemia. Moreover, steroids probably played an etiological role. Key Words: Nephrotic syndrome—Sinus venous throm bosis—Venous thrombosis—Antithrombin III.

Clinical and Applied Thrombosis/Hemostasis, Vol. 2, No. 2, 142-144 (1996)
DOI: 10.1177/107602969600200210
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