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Liver Cirrhosis Manifested by Dysfibrinogenemia

Hematology/Oncology, Department of Medicine, Texas A&M University Health Science Center College of Medicine and Olin E. Teague Veterans' Center, Temple, Texas, U.S.A.

We report a case in which liver cirrhosis was manifested by dysfibrinogenemia before the diagnosis of liver cirrhosis was made. A patient developed gastrointestinal bleeding and hepatic encephalopathy although liver function tests, prothrombin time (PT), activated partial thromboplastin time (aPTT), bleeding time, fibrin (ogen) degradation products (FDP), and platelet counts were normal. However, thrombin time (TT) was prolonged. The gastrointestinal bleeding (GI bleeding) was successfully treated with cryoprecipitate and fresh frozen plasma (FFP). Key Words: Dysfibrinogenemia—Liver disease—Thrombin time.

Clinical and Applied Thrombosis/Hemostasis, Vol. 3, No. 2, 102-103 (1997)
DOI: 10.1177/107602969700300206


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